After exclusion of prevalent users of NSAIDs and prevalent cases of TB in the 1 year pre-enrollment period, 123,419 person years were exposed to traditional NSAIDs and 16,392 person years were exposed to Coxibs. Health Affairs. 2003;22(3):77–88.View ArticlePubMedGoogle ScholarLee MS, Lin RY, Chang YT, Lai MS. The risk of developing non-melanoma skin cancer, lymphoma and melanoma in patients with psoriasis in Taiwan: a 10-year, population-based cohort study. Warranty, Returns, And Additional Information Through the Newegg EggXpert Review Program, Newegg invites its best reviewers, known as EggXperts, to post opinions about new and pre-release products to help their fellow customers make informed buying decisions.Click here for more details. The NHIRD database contains de-identified secondary data, and met the requirements of the “Personal Information Protection Act” in Taiwan. Any use of the raw data required a license agreement with the Bureau of National Health Insurance.
Nature. 1971;231(25):232–5.Google ScholarBombardier C, Laine L, Reicin A, Shapiro D, Burgos-Vargas R, Davis B, Day R, Ferraz MB, Hawkey CJ, Hochberg MC, VIGOR Study Group, et al. Index date referred to the first date of TB diagnosis. Can Med Assoc J. 1984;130(3):275.PubMedPubMed CentralGoogle ScholarBrassard P, Lowe AM, Bernatsky S, Kezouh A, Suissa S. Rheumatoid arthritis, its treatments, and the risk of tuberculosis in Quebec, Canada. Hence, we wish to investigate the influence of NSAIDs on active TB in the general population.Taiwan has one of the most affordable single-payer universal public health insurance and the claim history is completely recorded in a public database. Since we were using a claims database for our study, many lifestyle factors such as smoking, alcohol, and body mass index are missing. The first method, which is matching only on agegroup, gender, and calendar year, can be considered an unadjusted way of obtaining rate ratio (RR). The age-sex-year matched RR is 1.39 (95%CI, 1.24 – 1.57) for traditional NSAIDs and 1.40 (95%CI, 1.03 – 1.92) for Coxibs.
Our goal is to evaluate whether the use of non-steroidal anti-inflammatory drugs (NSAIDs) affect the risk of new incident active TB disease.We conducted a nested case-control analysis by using a 1 million longitudinally followed cohort, from Taiwan’s national health insurance research database. Coxibs users were found to increase steadily from 2001 to 2004. However, there is a sharp decline in Coxib users after 2004, when rofecoxib revealed safety concerns and was pulled off the market. Using ICD9-CM codes, the following covariates were assessed: age, sex, burden of comorbid conditions, indicators for frailty, risk factors for TB disease and use of specific medications.